2nd Infantry Regiment completed its organization at Brunswick, Georgia, in June, 1861, and moved to Virginia. Its companies were raised in the counties of Banks, Jackson, Muscogee, Burke, Bibb, Marion, and Stewart. In April, 1862, the regiment had a force of 607 men and during the war served in General Toombs' and Benning's Brigade. It fought with the Army of Northern Virginia from the Seven Days' Battles to Cold Harbor, except when it was detached with Longstreet at Suffolk, Chickamauga, and Knoxville. The 2nd was involved in the Petersburg siege south of the James River and various engagements around Appomattox. The seven companies that saw action at Garnett's lost forty-two percent of the 271 engaged, then reported 11 killed and 70 wounded at Malvern Hill. The unit lost thirty-four percent of the 163 at Second Manassas and twenty-eight percent of the 348 at Gettysburg. It sustained 66 casualties from April 14, to May 6, and 25 from August 1 to December 31, 1864. There were 12 officers and 146 men present at the surrender. Its commanders were Colonels Edgar M. Butt and Paul J. Semmes; Lieutenant Colonels Skidmore Harris, William T. Harris, William R. Holmes, and William S. Shephard; and Majors William W. Charlton and Abner M. Lewis.