46th Infantry Regiment, organized at Loachapoka, Alabama, in May, 1862, contained men from Randolph, Pike, Blount, Coosa, Macon, Montgomery, and Henry counties. Sent to East Tennessee, it sustained several casualties in the fight at Tazewell. After serving in the Kentucky Campaign, the unit was assigned to General Tracey's Brigade, Department of Mississippi and East Louisiana. A number of men were disabled at Port Gibson and about half were captured at Champion's Hill, including all its field officers. The remaining men were captured at Vicksburg on July 4, 1863. Exchanged and reorganized, the 46th was attached to General Pettus' Brigade and continued the fight with the Army of Tennessee. It was active at Chattanooga and Atlanta, moved with Hood to Tennessee, and saw action at Kinston and Bentonville. The regiment lost 15 killed and 45 wounded at Vicksburg and 1 killed and 14 wounded at Chattanooga. It totalled 367 men and 266 arms in December, 1863, had 174 present in January, 1865, and surrendered with no more than 75 in April. Colonel M.L. Woods, Lieutenant Colonel Osceola Kyle, and Majors George E. Brewer and J.M. Handley were in command.