Organized at Louisiana, Pike County, Mo., May 5, 1862. Guard line of the North Missouri Railroad and operations in Northeast Missouri against Porter till February, 1863. Prairie Jackson, Mo., April 9, 1862 (Cos. "A," "B" "C"). Near Fayetteville, Ark., July 15. Moore's Mills, near Fulton, July 24. Greenville July 26. Dallas August 24. Newtonia September 13. Monroe County September 16 and October 4. Operations against Marmaduke in Missouri December 31, 1862, to January 25, 1863. Springfield January 8, 1863. Regiment disbanded February 4. 1863.

Regiment lost during service 7 Enlisted men killed and mortally wounded and 3 Officers and 62 Enlisted men by disease. Total 72.