Thomas Wood was born around 1810 in Pennsylvania to William Wood and Grezel Dunlap. His father died around 1813. He married Margaret D. Beeber around 1834, and they had at least ten children: Elizabeth, born around 1835; Rachel, born around 1837; William, born around 1839; George, born around 1848; and six other children who died in infancy.
By 1850, they were living in Muncy Creek, Pennsylvania. Wood was working as a farmer, and he owned $10,000 of real estate. A decade later, he owned $15,000 of real estate and $1,500 of personal property, and by 1870, he had $21,000 of real estate and $3,000 of personal property. He died in Muncy Creek on February 12, 1884.