Organized at Camp Dennison, Ohio, August and September, 1862. Moved to Covington September 3, 1862, to repel Kirby Smith's threatened attack on Cincinnati, Ohio. Attached to 1st Brigade, 2nd Division, Army of Kentucky, Dept. of the Ohio, to December, 1862. 1st Brigade, 10th Division, 13th Army Corps (Old), Dept. of the Tennessee, December, 1862. 1st Brigade, 1st Division, Sherman's Yazoo Expedition, to January, 1863. 1st Brigade, 10th Division, 13th Army Corps, Army of the Tennessee, to August, 1863. 1st Brigade, 4th Division, 13th Army Corps, Army of the Tennessee, August, 1863, and Dept. of the Gulf to January, 1864. 2nd Brigade, 3rd Division, 13th Army Corps, Army of the Gulf, to March, 1864. 1st Brigade, 4th Division, 13th Army Corps, to June, 1864. 3rd Brigade, 3rd Division, 19th Army Corps, Dept. of the Gulf, to December, 1864. Post of Natchez, Miss., District of Vicksburg, Miss., to January, 1864. 3rd Brigade, Reserve Corps, Military Division West Mississippi, to February, 1865. 3rd Brigade, 2nd Division, Reserve Corps, February, 1865. 3rd Brigade, 2nd Division, 13th Army Corps (New), to July, 1865.

SERVICE:
Expedition to Cynthiana, Ky., September 18, 1862. Moved to Camp Shaler September 25, thence to Paris, Ky., October 15. To Louisville, Ky., October 28, and to Memphis, Tenn., November 23. Sherman's Yazoo Expedition December 20, 1862, to January 3, 1863. Expedition from Milliken's Bend to Dallas Station and Delhi, December 25-26. Chickasaw Bayou December 26-28. Chickasaw Bluff December 29. Expedition to Arkansas Post, Ark., January 3-10, 1863. Assault and capture of Fort Hindman, Arkansas Post, January 10-11. Moved to Young's Point, La., January 15, and duty there till March 10. Expedition to Greenville, Miss., and Cypress Bend, Ark., February 14-26. Deer Creek near Greenville February 23. At Milliken's Bend, La., till April 15. Movement on Bruinsburg and turning Grand Gulf April 25-30. Battle of Port Gibson May 1. Battle of Champion's Hill May 16. Big Black River May 17. Siege of Vicksburg, Miss., May 18-July 4. Assaults on Vicksburg May 19 and 22. Advance on Jackson, Miss., July 4-10. Siege of Jackson July 10-17. Camp at Vicksburg till August 24. Ordered to New Orleans, La., August 24. Expedition from Carrollton to New and Amite Rivers September 24-29. Moved to Brashear City. Western Louisiana Campaign October 3-November 30. Grand Coteau November 3. At New Iberia till December 19. Moved to New Orleans, La., thence to Madisonville January 19, 1864, and duty there till March. Red River Campaign March 10-May 22. Advance from Franklin to Alexandria March 14-26. Bayou de Paul and battle of Sabine Cross Roads April 8, 1864. Monett's Ferry, Cane River Crossing, April 23. Construction of dam at Alexandria April 30-May 10. Gov. Moore's Plantation May 2. Alexandria May 2-9. Retreat to Morganza May 13-20. Mansura May 16. Moved to Baton Rouge, La., May 28, and duty there till July 21. Moved to Morganza July 21, and duty there till November. Expedition to Morgan's Ferry October 1-9, and to the Atchafalaya October 18-29. At mouth of White River November 1-December 6. Moved to Natchez December 6 and duty there till January 28, 1865. Consolidated with 48th Ohio Infantry January 17, 1865. Moved to Kennersville, La., January 28, thence to New Orleans and to Barrancas, Fla. Campaign against Mobile, Ala., and its defences March-April. March from Pensacola, Fla., to Blakely, Ala., March 20-April 2. Occupation of Canoe Station March 27. Siege of Fort Blakely April 2-9. Assault and capture of Fort Blakely April 9. Capture of Mobile April 12. March to Montgomery and Selma April 13-25. Duty at Selma till May 12. Moved to Mobile May 12, thence to Galveston, Texas, June 13, and duty there till July 24. Veterans and Recruits transferred to 48th Ohio Infantry Battalion. Mustered out July 24, and discharged at Camp Dennison, Ohio, August 10, 1865.
Regiment lost during service 4 Officers and 52 Enlisted men killed and mortally wounded and 2 Officers and 161 Enlisted men by disease. Total 219.