15th Infantry Regiment completed its organization in September, 1861, at Lightwoodknot Springs, near Columbia, South Carolina. Its members were raised in the counties of Richland, Union, Lexington, Kershaw, Fairfield, and Williamsburg. After serving on James Island, the unit moved to Virginia and was assigned to General Drayton's, Kershaw's, Kennedy's, and Conner's Brigade. The 15th participated in the campaigns of the Army of Northern Virginia from Second Manassas to Gettysburg, then fought with Longstreet at Chickamauga and Knoxville. It returned to Virginia, saw action at The Wilderness, Spotsylvania, and Cold Harbor, and later was involved in Early's Shenandoah Valley operations and the North Carolina Campaign. This regiment sustained 24 casualties at Second Manassas, 110 at Sharpsburg, 55 out of 404 at Fredericksburg, 54 at Chancellorsville, and 137 of the 448 at Gettysburg. It reported 3 killed and 11 wounded at Knoxville and had 1 wounded at Bentonville. On March 23, 1865, it contained 162 men and surrendered on April 26. The field officers were Colonels John B. Davis, William D. De Saussure, and Joseph F. Gist; Lieutenant Colonels Richard Anderson and Frederick S. Lewie; and Major William M. Gist.