5th Infantry Regiment, assembled during March and April, 1861, contained men recruited in Laruens, Lancaster, Spartanburg, and Union counties. It was ordered to Virginia and, serving in D.R. Jones' Brigade, saw action at First Manassas. Later it was placed in General R.H. Anderson's, M. Jenkins', and Bratton's Brigade. It participated in the campaigns of the army from Williamsburg to Fredericksburg, then served in Longstreet's Suffolk operations and with D.H. Hill in North Carolina. Moving again with Longstreet, the unit did not arrive in time to take part in the Battle of Chickamauga, but was engaged at Knoxville. Returning to Virginia, it was conspicuous at The Wilderness, Spotsylvania, and Cold Harbor, in the trenches of Petersburg, and around Appomattox. This regiment reported 3 killed and 23 wounded at First Manassas and totalled 650 men in April, 1862. It sustained 21 casualties at Williamsburg, 81 at Gaines' Mill, 73 at Frayser's Farm, 39 during the Maryland Campaign, and 102 at Wauhatchie. In 1864 it lost 18 killed, 95 wounded, and 16 missing during The Wilderness Campaign, and from June 13 to December 31, there were 11 killed and 65 wounded. On April 9, 1865, the unit surrendered 19 officers and 263 men. The field officers were Colonels A. Coward, John R.R. Giles, and Micah Jenkins; Lieutenant Colonels Andrew Jackson, G.W.H. Legg, and John D. Wylie; and Majors Thomas C. Beckham, William M. Foster, and William T. Thomson.