Guadelupe McDonald was born around 1862 in Texas. She grew up in her uncle William Adams’ household in San Felipe, Texas. He worked as a farmer, and by 1870, he owned $3,000 of real estate and $20,000 of personal property. They moved to San Antonio, Texas, in the 1870s. She married Matthew T. Hendricks on August 11, 1886, and she died on May 7, 1888.