Palmetto Regiment Sharpshooters was organized in April, 1862, with transfers from the 2nd, 5th, and 9th South Carolina Infantry Regiments. Send to Virginia, the unit was assigned to General R.H. Anderson's, Jenkins', and Bratton's Brigade. It fought with the army from Williamsburg to Fredericksburg, served at Suffolk and in North Carolina, then saw action at Chickamauga and Knoxville. Returning to Virginia, it continued the fight at The Wilderness, Spotsylvania, and Cold Harbor, endured the hardships of the Petersburg trenches, and ended the war at Appomattox. It lost 9 killed and 74 wounded at Gaines' Mill and sixty-eight percent of the 375 engaged at Frayser's Farm. The regiment reported 2 casualties at South Mountain, 65 at Sharpsburg, 4 at Fredericksburg, and 44 at Wauhatchie. It surrendered 29 officers and 356 men. The field officers were Colonels Micah Jenkins and Joseph Walker; Lieutenant Colonel John W. Goss; and Majors William Anderson, William W. Humphreys, and Franklin W. Kilpatrick.