John Edwin Pierce was born on March 16, 1854, in East Boston, Massachusetts, to Edwin R. Pierce and Juliette Merrill. His father was a contractor who owned $1,000 of real estate and $500 of personal property by 1860. Pierce grew up and attended school in Boston, and he graduated from the English High School in 1871. According to a local writer, he “received a Benjamin Franklin medal for good scholarship.” He passed the examinations for the Massachusetts Institute of Technology, but he apparently chose not to enroll.
Instead, Pierce worked as an architect for two years before beginning work as a clerk at the Suffolk Savings Bank. He married Margaret L. Gammon on June 16, 1892, and they had at least three children: John, born around 1893; Edwin, born around 1896; and Abbot, born around 1908. They lived in Lynn, Massachusetts, and Pierce continued to earn a living as a bank clerk. They moved to Barnet, Vermont, in the 1910s.He died of chronic myocarditis and arteriosclerosis in Barnet on March 12, 1928.