Louise Kimball Hopkins was born around 1834 in Pennsylvania. She married Commodore William Evelyn Hopkins on March 30, 1852, at St. Luke's Protestant Episcopal Church in Philadelphia. Following their marriage, the couple lived with his mother, Abby B. Hopkins, in Winchester, Virginia. They had eight children: Mariah B., born around 1853; Jennett D., born around 1856, who died between 1860 and 1870; William Evelyn, Jr., born around 1859; Louise, born and died between 1860 and 1870; Abby P., born around 1860; Henry St. George, born around 1863; Edward "Ned" K., born around 1869; and John P., born around 1871. Following her husband's death on October 24, 1894, she filed for a navy widow's pension. The pension was issued on April 2, 1895, allowing her to receive $30 a month backdated to begin immediately after her husband's death. She died on January 5, 1901, in Ross Valley, California, and is buried alongside her husband in the Mountain View Cemetery in Oakland.