George Rutherford was born around 1841 in Galena, Ohio, to John and Sarah Rutherford. His father was a farmer who owned $500 of real estate by 1850. He grew up and attended school in Genoa, Ohio. He moved to Minneapolis, Minnesota, around 1859 and reportedly worked on “one of the steamers plying the river.”
He enlisted in the Union army on July 8, 1861, and he mustered in as a private in Company F of the 2nd Minnesota Infantry. The regiment took part in the siege of Corinth, the Battle of Perryville, the Tullahoma campaign, the Battle of Chickamauga, and the Atlanta campaign. He eventually earned a promotion to sergeant. He remained devoted to the Union. In March 1864, as he prepared for battle, he declared that "we gladly goe forth to fight for the old flag of our country the emblem of a free people." He was severely wounded in the left shoulder in the Battle of Kennesaw Mountain in June 1864, and he mustered out on June 21, 1865.
He returned to St. Anthony after the war. He applied for a federal pension in August 1865 and eventually secured one. He married Elizabeth M. Millen on March 24, 1867, and they had at least four children: Fanny, born around 1868; Harry, born around 1871; W., born around 1875; and George, born around 1880. They moved to Wisconsin and then to Le Claire, Iowa, in the 1870s. By 1880, he was working as a master pilot with the Le Claire Navigation Company. The family returned to Minneapolis in the 1880s. He died there of heart disease on July 4, 1895.