John Loughran was born around 1838, either in Ireland or New Jersey, to James and Sarah Loughran. His father was a stonecutter. By 1860, he was working as a stonecutter in New York City.
He enlisted in the Union army on September 23, 1861, and he mustered in as a corporal in Company F of the 57th New York Infantry. He received a gunshot wound in the Battle of Seven Pines on June 1, 1862. According to his commanding officer, “the ball entered his cheek and I understand came out at the mouth.” Union officials sent him north to recover, and he apparently died soon afterward. His sister Rose tried to determine his fate, corresponding with surgeons in Annapolis, Baltimore, Philadelphia, and New York, but to no avail.